AOD-9604 (10mg) Research Profile: Investigating Lipolytic Signaling and Pituitary-Independent Metabolism
AOD-9604 (Advanced Obesity Drug 9604) is a synthetic analog of the lipolytic C-terminal region of human Growth Hormone ($hGH\ 177-191$), featuring a stabilizing disulfide bond between the C-terminal cysteine residues. In 2026 life sciences research, this compound represents a key model for analyzing targeted fat metabolism because it isolates lipolytic pathways without initiating IGF-1 transcription or cross-reacting with systemic insulin-like growth factor receptors. Institutions choosing to buy AOD-9604 (10mg) online trust Peptide Crafters for analytical transparency and batch-specific lab reports.
Molecular Specifications
| Parameter | Specification |
| Amino Acid Sequence | $Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe$ (with variable modifications) |
| Molecular Formula | $C_{78}H_{123}N_{23}O_{23}S_{2}$ |
| Molecular Weight | $1815.1\ g/mol$ |
| CAS Number | 221231-10-3 |
| Structure | Synthetic cyclic peptide fragment (Acetate Salt) |
| Purity Grade | 99%+ Analytical Standard |
Pharmacokinetic Horizons
-
Selective Ligand-Receptor Affinity for Beta-3 Adrenergic Pathways: AOD-9604 is extensively utilized for Analyzing the binding affinity at the beta-3 adrenergic receptor (β3-AR) complex, exploring the downstream stimulation of adenylate cyclase and the subsequent induction of lipolysis in localized adipocyte tissue cultures.
-
Proteolytic Mitigation via Disulfide Cyclization: The molecule incorporates a custom disulfide bridge between internal residues, ensuring high-fidelity Proteolytic Mitigation against rapid systemic endopeptidase degradation during long-term in-vitro incubation assays.
-
Non-Mitogenic Cellular Transduction: Studies focus on the peptide’s structural truncation, demonstrating that its Cellular Transduction cascades stimulate cyclic AMP ($cAMP$) and protein kinase A (PKA) activity without binding to the human growth hormone receptor (hGHR) complex, thus bypassing insulin-resistance and proliferative pathways.
Why Procure from Peptide Crafters?
-
ISO-Certified HPLC Identification: Every batch from this peptide crafter undergoes strict reverse-phase HPLC and mass spectrometry analysis to guarantee absolute sequence purity and zero batch-to-batch variance.
-
60-Day Money-Back Quality Guarantee: We back our inventory with a 60-day assurance program, showcasing the precision and structural fidelity of our lab tested peptides.
-
Vacuum-Sealed Lyophilized Preservation: Our vials are deep-frozen and moisture-extracted in sterile environments to guarantee long-term stability when you buy peptides online.
-
Institutional Standards Compliance: While research teams may apply a peptide crafters discount code for allocation efficiency, the core benefit lies in our adherence to USP 85 endotoxin limitations, minimizing noise in sensitive laboratory models.
For comprehensive biochemical parameters, navigate to the official peptide crafters catalog. Utilizing an official peptide crafters discount code during checkout enables institutions to obtain pristine reagents while effectively managing specialized funding targets.
Research Use Only: All Peptide Crafters products are strictly for in-vitro laboratory research. Not for human or veterinary use. Communication regarding bodily administration will result in an immediate account termination.
