MOTS-c Research Profile: Investigating Mitochondrial Open Reading Frame Signaling Pathways
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) represents a paradigm shift in endocrinology and cellular biology, highlighting autonomous nuclear-mitochondrial communication pathways. In 2026 life sciences research, this mitochondrial-derived peptide (MDP) is utilized as a vital model to investigate systematic energy sensing, adaptive metabolic plasticity, and insulin-mimetic glucose utilization at the cellular level. Institutions choosing to buy MOTS-c online trust Peptide Crafters for analytical transparency and batch-specific lab reports.
Molecular Specifications
| Parameter | Specification |
| Amino Acid Sequence | $Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Leu-Pro-Arg-Lys-Leu-Arg$ |
| Molecular Formula | $C_{101}H_{167}N_{31}O_{23}S_{2}$ |
| Molecular Weight | $2175.7\ g/mol$ |
| CAS Number | 1627503-51-9 |
| Structure | Synthetic linear mitochondrial-derived peptide (Acetate Salt) |
| Purity Grade | 99%+ Analytical Standard |
Pharmacokinetic Horizons
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Indirect Ligand-Receptor Affinity and AICAR-like Expression: MOTS-c is used for Analyzing the binding affinity at the AMPK (AMP-activated protein kinase) complex, looking at how it behaves as an upstream modulator to initiate metabolic responses reminiscent of classic AICAR pathways without binding to surface growth hormone pathways.
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Proteolytic Mitigation of Serum Endopeptidases: Because of its linear layout, our sophisticated multi-stage purification delivers essential Proteolytic Mitigation, reinforcing the stability of the molecular backbone during extended in-vitro incubation parameters studying cellular respiration.
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Intracellular Cellular Transduction Flux and Glut4 Translocation: Research focuses on the peptide’s distinct Cellular Transduction signaling, tracking its movement into the nucleus under cellular stress to alter transcriptional activity and stimulate the expression of glucose transporter 4 (GLUT4) independent of insulin receptor binding.
Why Procure from Peptide Crafters?
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ISO-Certified HPLC Identification: Every batch from this peptide crafter undergoes thorough high-performance liquid chromatography and mass spectrometry matching to establish absolute sequence sequence integrity.
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60-Day Money-Back Quality Guarantee: We back our scientific catalog with an robust 60-day replacement window, a standard consistently verified across independent peptide crafters reviews.
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Vacuum-Sealed Lyophilized Preservation: Reagents undergo deep moisture extraction and are nitrogen-flushed to preserve chemical integrity when you buy peptides online.
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Institutional Security: While laboratories frequently apply an official peptide crafters coupon code or a peptide crafters discount code to match institutional budgets, the baseline value is found in our strict adherence to USP 71/85 sterilization criteria.
For comprehensive sequence packages and inventory requests, explore the official peptide crafters portal. Utilizing an active peptide crafters coupon code during procurement checkouts assists scientific operations in securing pristine research materials within expected financial frameworks.
Research Use Only: All Peptide Crafters products are strictly for in-vitro laboratory research. Not for human or veterinary use. Communication regarding bodily administration will result in an immediate account termination.




